{"id":357,"date":"2023-05-11T18:03:08","date_gmt":"2023-05-11T11:03:08","guid":{"rendered":"https:\/\/genestory.ai\/blog\/?post_type=news&p=357"},"modified":"2023-05-19T14:14:50","modified_gmt":"2023-05-19T07:14:50","slug":"pgs-ts-nguyen-lan-hieu-nguoi-ngheo-cung-phai-duoc-huong-loi-tu-cac-thanh-tuu-khoa-hoc","status":"publish","type":"news","link":"https:\/\/genestory.ai\/blog\/index.php\/news\/pgs-ts-nguyen-lan-hieu-nguoi-ngheo-cung-phai-duoc-huong-loi-tu-cac-thanh-tuu-khoa-hoc\/","title":{"rendered":"\u201cNg\u01b0\u1eddi ngh\u00e8o c\u0169ng ph\u1ea3i \u0111\u01b0\u1ee3c h\u01b0\u1edfng l\u1ee3i t\u1eeb c\u00e1c th\u00e0nh t\u1ef1u khoa h\u1ecdc\u201d"},"content":{"rendered":"\n

Ng\u00e0y 09.05 v\u1eeba qua, Ch\u01b0\u01a1ng tr\u00ecnh \u0111\u00e0o t\u1ea1o li\u00ean t\u1ee5c: C\u00c1 TH\u1ec2 H\u00d3A \u0110I\u1ec0U TR\u1eca D\u1ef0A TR\u00caN DI TRUY\u1ec0N D\u01af\u1ee2C L\u00dd t\u1ed5 ch\u1ee9c b\u1edfi B\u1ec7nh vi\u1ec7n \u0110\u1ea1i h\u1ecdc Y H\u00e0 N\u1ed9i \u0111\u00e3 thu h\u00fat h\u01a1n 100 h\u1ecdc vi\u00ean l\u00e0 c\u00e1c b\u00e1c s\u0129, d\u01b0\u1ee3c s\u0129 v\u00e0 nh\u00e2n vi\u00ean y t\u1ebf tham d\u1ef1. GeneStory v\u00e0 Qu\u1ef9 \u0110\u1ed5i m\u1edbi s\u00e1ng t\u1ea1o Vingroup (VinIF) h\u00e2n h\u1ea1nh \u0111\u1ed3ng h\u00e0nh c\u00f9ng ch\u01b0\u01a1ng tr\u00ecnh v\u1edbi t\u01b0 c\u00e1ch nh\u00e0 t\u00e0i tr\u1ee3.<\/p>\n\n\n

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Ch\u01b0\u01a1ng tr\u00ecnh \u0111\u00e0o t\u1ea1o li\u00ean t\u1ee5c: C\u00e1 th\u1ec3 h\u00f3a \u0111i\u1ec1u tr\u1ecb d\u1ef1a tr\u00ean di truy\u1ec1n d\u01b0\u1ee3c l\u00fd thu h\u00fat h\u01a1n 100 h\u1ecdc vi\u00ean l\u00e0 c\u00e1c B\u00e1c s\u0129, D\u01b0\u1ee3c s\u0129 v\u00e0 nh\u00e2n vi\u00ean y t\u1ebf<\/em><\/figcaption><\/figure><\/div>\n\n\n

Ph\u00e1t bi\u1ec3u khai m\u1ea1c ch\u01b0\u01a1ng tr\u00ecnh, PGS.TS Nguy\u1ec5n L\u00e2n Hi\u1ebfu – Gi\u00e1m \u0111\u1ed1c B\u1ec7nh vi\u1ec7n \u0110\u1ea1i h\u1ecdc Y H\u00e0 N\u1ed9i cho r\u1eb1ng, kh\u00f4ng ch\u1ec9 l\u00e0 m\u1ed9t ch\u01b0\u01a1ng tr\u00ecnh \u0111\u00e0o t\u1ea1o, \u0111\u00e2y l\u00e0 m\u1ed9t \u201cdi\u1ec5n \u0111\u00e0n m\u1edf\u201d d\u00e0nh cho c\u00e1c chuy\u00ean gia, b\u00e1c s\u0129 quan t\u00e2m v\u00e0 \u0111ang l\u00e0m vi\u1ec7c trong l\u0129nh v\u1ef1c di truy\u1ec1n v\u00e0 chuy\u1ec3n h\u00f3a c\u00f9ng nhau trao \u0111\u1ed5i v\u00e0 c\u1eadp nh\u1eadt ki\u1ebfn th\u1ee9c.<\/p>\n\n\n\n

Ch\u1ee7 t\u1ecda, \u0111\u1ed3ng th\u1eddi l\u00e0 m\u1ed9t trong 4 gi\u1ea3ng vi\u00ean c\u1ee7a bu\u1ed5i h\u1ecdc, PGS.TS Nguy\u1ec5n L\u00e2n Hi\u1ebfu \u0111\u01b0a ra th\u00f4ng tin c\u00f3 t\u1edbi 57% c\u00e1c lo\u1ea1i thu\u1ed1c trong danh s\u00e1ch top 20 g\u00e2y ra nguy c\u01a1 ph\u1ea3n \u1ee9ng c\u00f3 h\u1ea1i c\u00f3 li\u00ean quan t\u1edbi bi\u1ebfn th\u1ec3 v\u1ec1 di truy\u1ec1n; v\u00e0 c\u00f3 250 lo\u1ea1i thu\u1ed1c \u0111\u01b0\u1ee3c FDA d\u00e1n nh\u00e3n c\u1ea3nh b\u00e1o li\u00ean quan t\u1edbi gen. \u0110\u00e2y l\u00e0 bi\u1ec3u hi\u1ec7n t\u00ednh c\u00e1 th\u1ec3 h\u00f3a trong \u0111i\u1ec1u tr\u1ecb b\u1eb1ng thu\u1ed1c (k\u00ea \u0111\u01a1n thu\u1ed1c d\u1ef1a tr\u00ean ki\u1ec3u gen ng\u01b0\u1eddi b\u1ec7nh) c\u0169ng nh\u01b0 s\u1ef1 c\u00f4ng nh\u1eadn v\u00e0 \u1ee9ng d\u1ee5ng d\u01b0\u1ee3c l\u00fd di truy\u1ec1n trong l\u00e2m s\u00e0ng c\u1ee7a y khoa th\u1ebf gi\u1edbi. Trong khi \u0111\u00f3, t\u1ea1i Vi\u1ec7t Nam x\u00e9t nghi\u1ec7m d\u01b0\u1ee3c l\u00fd di truy\u1ec1n v\u1ec1 kh\u1ea3 n\u0103ng \u0111\u00e1p \u1ee9ng thu\u1ed1c v\u1eabn c\u00f2n l\u00e0 m\u1ed9t l\u0129nh v\u1ef1c m\u1edbi m\u1ebb. <\/p>\n\n\n

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Th\u00f4ng tin t\u1eeb PGS.TS Nguy\u1ec5n L\u00e2n Hi\u1ebfu \u0111\u01b0a ra c\u00f3 t\u1edbi 57% c\u00e1c lo\u1ea1i thu\u1ed1c trong danh s\u00e1ch top 20 g\u00e2y ra nguy c\u01a1 ph\u1ea3n \u1ee9ng c\u00f3 h\u1ea1i c\u00f3 li\u00ean quan t\u1edbi bi\u1ebfn th\u1ec3 v\u1ec1 di truy\u1ec1n; v\u00e0 c\u00f3 250 lo\u1ea1i thu\u1ed1c \u0111\u01b0\u1ee3c FDA d\u00e1n nh\u00e3n c\u1ea3nh b\u00e1o li\u00ean quan t\u1edbi gen<\/em><\/figcaption><\/figure><\/div>\n\n\n

Th\u1ef1c t\u1ebf l\u00e2m s\u00e0ng c\u0169ng \u0111\u00e3 ghi nh\u1eadn c\u00e1c ca s\u1eed d\u1ee5ng clopidogrel (thu\u1ed1c ch\u1ed1ng k\u1ebft t\u1eadp ti\u1ec3u c\u1ea7u, d\u00f9ng cho b\u1ec7nh nh\u00e2n \u0111\u1eb7t stent m\u1ea1ch v\u00e0nh) li\u1ec1u r\u1ea5t th\u1ea5p nh\u01b0ng v\u1eabn g\u00e2y ch\u1ea3y m\u00e1u, v\u00e0 ng\u01b0\u1ee3c l\u1ea1i, s\u1eed d\u1ee5ng li\u1ec1u cao nh\u01b0ng l\u1ea1i t\u1eafc m\u1ea1ch, g\u00e2y ra nhi\u1ec1u b\u1ed1i r\u1ed1i cho b\u00e1c s\u0129. Khi \u0111\u00f3, vai tr\u00f2 c\u1ee7a c\u00e1c y\u1ebfu t\u1ed1 ph\u1ee5 tr\u1ee3 nh\u01b0 x\u00e9t nghi\u1ec7m gen l\u00e0 r\u1ea5t quan tr\u1ecdng gi\u00fap c\u00e1c b\u00e1c s\u0129 ra quy\u1ebft \u0111\u1ecbnh \u0111i\u1ec1u tr\u1ecb hi\u1ec7u qu\u1ea3.<\/p>\n\n\n\n

BS Chu Ch\u00ed Hi\u1ebfu – Tr\u01b0\u1edfng ph\u00f2ng d\u1ecb nguy\u00ean – Trung t\u00e2m D\u1ecb \u1ee9ng mi\u1ec5n d\u1ecbch, B\u1ec7nh vi\u1ec7n B\u1ea1ch Mai c\u0169ng cho bi\u1ebft, m\u1ed9t s\u1ed1 n\u01a1i tr\u00ean th\u1ebf gi\u1edbi nh\u01b0 \u1edf ch\u00e2u \u00c2u, Hoa K\u00ec, y\u00eau c\u1ea7u s\u00e0ng l\u1ecdc gen tr\u01b0\u1edbc khi k\u00ea \u0111\u01a1n m\u1ed9t s\u1ed1 lo\u1ea1i thu\u1ed1c \u0111\u00e3 \u0111\u01b0\u1ee3c \u0111\u01b0a v\u00e0o lu\u1eadt, ti\u00eau bi\u1ec3u l\u00e0 v\u1edbi thu\u1ed1c \u0111i\u1ec1u tr\u1ecb g\u00fat (allopurinol) v\u00e0 thu\u1ed1c \u0111i\u1ec1u tr\u1ecb \u0111\u1ed9ng kinh (carbamazepine). T\u1ea1i Vi\u1ec7t Nam, c\u00e1c nghi\u00ean c\u1ee9u hi\u1ec7n \u0111\u00e3 \u0111\u1ea7y \u0111\u1ee7 v\u00e0 s\u1eb5n s\u00e0ng, tuy nhi\u00ean r\u1ea5t c\u1ea7n s\u1ef1 tham gia c\u1ee7a c\u00e1c c\u01a1 quan chuy\u00ean tr\u00e1ch \u0111\u1ec3 x\u00e9t nghi\u1ec7m s\u00e0ng l\u1ecdc d\u01b0\u1ee3c l\u00fd di truy\u1ec1n \u0111\u01b0\u1ee3c \u0111\u01b0a v\u00e0o c\u00e1c khuy\u1ebfn c\u00e1o y khoa, t\u1eeb \u0111\u00f3 \u0111\u01b0\u1ee3c \u1ee9ng d\u1ee5ng r\u1ed9ng r\u00e3i h\u01a1n trong l\u00e2m s\u00e0ng.<\/p>\n\n\n

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Ch\u01b0\u01a1ng tr\u00ecnh \u0111\u00e0o t\u1ea1o l\u00e0 m\u1ed9t \u201cdi\u1ec5n \u0111\u00e0n m\u1edf\u201d d\u00e0nh cho c\u00e1c chuy\u00ean gia, b\u00e1c s\u0129 quan t\u00e2m v\u00e0 \u0111ang l\u00e0m vi\u1ec7c trong l\u0129nh v\u1ef1c di truy\u1ec1n v\u00e0 chuy\u1ec3n h\u00f3a c\u00f9ng nhau trao \u0111\u1ed5i v\u00e0 c\u1eadp nh\u1eadt ki\u1ebfn th\u1ee9c. <\/em><\/figcaption><\/figure><\/div>\n\n\n

B\u00ean c\u1ea1nh \u0111\u00f3, c\u00e1c b\u00e0i gi\u1ea3ng c\u00f3 t\u00ednh t\u1ed5ng qu\u00e1t v\u1ec1 m\u1ed1i t\u01b0\u01a1ng quan gi\u1eefa di truy\u1ec1n v\u00e0 thu\u1ed1c bao g\u1ed3m \u201c\u0110\u1ea1i c\u01b0\u01a1ng d\u01b0\u1ee3c \u0111\u1ed9ng h\u1ecdc – d\u01b0\u1ee3c l\u1ef1c h\u1ecdc – t\u01b0\u01a1ng t\u00e1c thu\u1ed1c – d\u01b0\u1ee3c l\u00fd di truy\u1ec1n\u201d tr\u00ecnh b\u00e0y b\u1edfi PGS.TS Ph\u1ea1m Th\u1ecb V\u00e2n Anh – Gi\u00e1m \u0111\u1ed1c Trung t\u00e2m D\u01b0\u1ee3c l\u00ed l\u00e2m s\u00e0ng – tr\u01b0\u1eddng \u0110\u1ea1i h\u1ecdc Y H\u00e0 N\u1ed9i v\u00e0 \u201cH\u1ec7 gen d\u01b0\u1ee3c l\u00fd trong th\u1ef1c h\u00e0nh l\u00e2m s\u00e0ng\u201d tr\u00ecnh b\u00e0y b\u1edfi PGS.TS L\u01b0\u01a1ng Th\u1ecb Lan Anh – Gi\u00e1m \u0111\u1ed1c Trung t\u00e2m Di truy\u1ec1n l\u00e2m s\u00e0ng, B\u1ec7nh vi\u1ec7n \u0110\u1ea1i h\u1ecdc Y H\u00e0 N\u1ed9i v\u1edbi v\u00ed d\u1ee5 \u0111i\u1ec3n h\u00ecnh v\u1ec1 h\u1ec7 gen chuy\u1ec3n h\u00f3a CYP450 v\u00e0 nh\u1eefng b\u1eb1ng ch\u1ee9ng v\u1ec1 s\u1ef1 t\u00e1c \u0111\u1ed9ng c\u1ee7a gen trong qu\u00e1 tr\u00ecnh chuy\u1ec3n h\u00f3a thu\u1ed1c l\u00e0 n\u1ec1n t\u1ea3ng \u0111\u1ec3 c\u00e1c h\u1ecdc vi\u00ean ti\u1ebfp t\u1ee5c \u0111\u00e0o s\u00e2u nghi\u00ean c\u1ee9u v\u00e0 \u0111\u01b0a v\u00e0o \u1ee9ng d\u1ee5ng th\u1ef1c ti\u1ec5n. <\/p>\n\n\n

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\u00d4ng Nguy\u1ec5n \u0110\u1ee9c Long – T\u1ed5ng Gi\u00e1m \u0111\u1ed1c ki\u00eam \u0111\u1ed3ng s\u00e1ng l\u1eadp GeneStory, cho bi\u1ebft hi\u1ec7n GeneStory \u0111ang tri\u1ec3n khai Ch\u01b0\u01a1ng tr\u00ecnh s\u00e0ng l\u1ecdc mi\u1ec5n ph\u00ed cho 3.000 b\u1ec7nh nhi c\u00f3 ho\u00e0n c\u1ea3nh kh\u00f3 kh\u0103n c\u00f3 nguy c\u01a1 m\u1eafc \u0111\u1ed9ng kinh tr\u00ean c\u1ea3 n\u01b0\u1edbc.<\/em><\/figcaption><\/figure><\/div>\n\n\n

C\u0169ng trong khu\u00f4n kh\u1ed5 ch\u01b0\u01a1ng tr\u00ecnh, \u00f4ng Nguy\u1ec5n \u0110\u1ee9c Long – T\u1ed5ng Gi\u00e1m \u0111\u1ed1c ki\u00eam \u0111\u1ed3ng s\u00e1ng l\u1eadp GeneStory, \u0111\u1ea1i di\u1ec7n \u0111\u01a1n v\u1ecb t\u00e0i tr\u1ee3, cho bi\u1ebft GeneStory hi\u1ec7n \u0111ang tri\u1ec3n khai ch\u01b0\u01a1ng tr\u00ecnh s\u00e0ng l\u1ecdc mi\u1ec5n ph\u00ed , t\u1ea1o h\u1ed3 s\u01a1 gen c\u00e1 nh\u00e2n v\u1ec1 thu\u1ed1c cho 3.000 b\u1ec7nh nhi c\u00f3 ho\u00e0n c\u1ea3nh kh\u00f3 kh\u0103n c\u00f3 nguy c\u01a1 m\u1eafc \u0111\u1ed9ng kinh tr\u00ean c\u1ea3 n\u01b0\u1edbc, h\u01b0\u1edbng t\u1edbi m\u1ee5c ti\u00eau \u0111\u01b0a l\u1ee3i \u00edch c\u1ee7a gi\u1ea3i m\u00e3 gen t\u1edbi g\u1ea7n h\u01a1n v\u1edbi ph\u1ea7n \u0111\u00f4ng ng\u01b0\u1eddi d\u00e2n. \u0110\u00e2y ph\u1ea7n n\u00e0o c\u0169ng l\u00e0 l\u1eddi gi\u1ea3i \u0111\u00e1p c\u1ee7a GeneStory cho b\u00e0i to\u00e1n m\u00e0 ch\u1ee7 t\u1ecda v\u00e0 gi\u1ea3ng vi\u00ean \u0111\u00e3 \u0111\u1eb7t ra t\u1eeb \u0111\u1ea7u bu\u1ed5i h\u1ecdc, v\u1ec1 vi\u1ec7c c\u00e1c \u0111\u01a1n v\u1ecb gi\u1ea3i m\u00e3 gen ph\u1ea3i t\u00ednh to\u00e1n v\u00e0 ph\u00e1t tri\u1ec3n s\u1ea3n ph\u1ea9m sao cho t\u1ed1i \u01b0u l\u1ee3i \u00edch kinh t\u1ebf cho ng\u01b0\u1eddi d\u00e2n, \u0111\u1ec3 cho \u201dng\u01b0\u1eddi ngh\u00e8o c\u0169ng ph\u1ea3i \u0111\u01b0\u1ee3c h\u01b0\u1edfng l\u1ee3i t\u1eeb c\u00e1c th\u00e0nh t\u1ef1u khoa h\u1ecdc.\u201d<\/p>\n\n\n\n

*******<\/p>\n\n\n\n

GeneStory xin g\u1eedi l\u1eddi c\u1ea3m \u01a1n ch\u00e2n th\u00e0nh t\u1edbi Qu\u1ef9 \u0110\u1ed5i m\u1edbi s\u00e1ng t\u1ea1o Vingroup (VinIF) \u0111\u00e3 c\u00f3 chung t\u1ea7m nh\u00ecn v\u1ec1 y h\u1ecdc d\u1ef1 ph\u00f2ng v\u00e0 tham gia ch\u01b0\u01a1ng tr\u00ecnh v\u1edbi t\u01b0 c\u00e1ch l\u00e0 nh\u00e0 \u0111\u1ed3ng t\u00e0i tr\u1ee3. GeneStory hi v\u1ecdng ti\u1ebfp t\u1ee5c nh\u1eadn \u0111\u01b0\u1ee3c s\u1ef1 \u0111\u1ed3ng h\u00e0nh c\u1ee7a VinIF trong c\u00e1c ho\u1ea1t \u0111\u1ed9ng th\u00fac \u0111\u1ea9y th\u1ef1c hi\u1ec7n nghi\u00ean c\u1ee9u khoa h\u1ecdc, c\u00f4ng ngh\u1ec7 v\u00e0 \u0111\u1ed5i m\u1edbi s\u00e1ng t\u1ea1o s\u00e1ng t\u1ea1o khoa h\u1ecdc kh\u00e1c trong t\u01b0\u01a1ng lai.<\/p>\n","protected":false},"excerpt":{"rendered":"

Ng\u00e0y 09.05 v\u1eeba qua, Ch\u01b0\u01a1ng tr\u00ecnh \u0111\u00e0o t\u1ea1o li\u00ean t\u1ee5c: C\u00c1 TH\u1ec2 H\u00d3A \u0110I\u1ec0U TR\u1eca D\u1ef0A TR\u00caN DI TRUY\u1ec0N D\u01af\u1ee2C L\u00dd t\u1ed5 ch\u1ee9c b\u1edfi B\u1ec7nh vi\u1ec7n \u0110\u1ea1i h\u1ecdc Y H\u00e0 N\u1ed9i \u0111\u00e3 thu h\u00fat h\u01a1n 100 h\u1ecdc vi\u00ean l\u00e0 c\u00e1c b\u00e1c s\u0129, d\u01b0\u1ee3c s\u0129 v\u00e0 nh\u00e2n vi\u00ean y t\u1ebf tham d\u1ef1. GeneStory v\u00e0 Qu\u1ef9 \u0110\u1ed5i…[\u0110\u1ecdc th\u00eam]<\/a><\/p>\n","protected":false},"author":2,"featured_media":353,"comment_status":"open","ping_status":"open","template":"","format":"standard","meta":[],"categories":[46],"tags":[21,20,23],"yoast_head":"\n\u201cNg\u01b0\u1eddi ngh\u00e8o c\u0169ng ph\u1ea3i \u0111\u01b0\u1ee3c h\u01b0\u1edfng l\u1ee3i t\u1eeb c\u00e1c th\u00e0nh t\u1ef1u khoa h\u1ecdc\u201d - Genestory Blog<\/title>\n<meta name=\"description\" content=\"Ng\u00e0y 09.05 v\u1eeba qua, Ch\u01b0\u01a1ng tr\u00ecnh \u0111\u00e0o t\u1ea1o li\u00ean t\u1ee5c: C\u00c1 TH\u1ec2 H\u00d3A \u0110I\u1ec0U TR\u1eca D\u01afA TR\u00caN DI TRUY\u1ec0N D\u01af\u1ee2C L\u00dd t\u1ed5 ch\u1ee9c b\u1edfi B\u1ec7nh vi\u1ec7n \u0110\u1ea1i h\u1ecdc Y H\u00e0 N\u1ed9i, t\u00e0i tr\u1ee3 b\u1edfi GeneStory v\u00e0 Qu\u1ef9 \u0110\u1ed5i m\u1edbi s\u00e1ng t\u1ea1o Vingroup (VinIF) \u0111\u00e3 thu h\u00fat h\u01a1n 100 h\u1ecdc vi\u00ean l\u00e0 c\u00e1c b\u00e1c s\u0129, d\u01b0\u1ee3c s\u0129 v\u00e0 nh\u00e2n vi\u00ean y t\u1ebf tham d\u1ef1.\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/genestory.ai\/blog\/index.php\/news\/pgs-ts-nguyen-lan-hieu-nguoi-ngheo-cung-phai-duoc-huong-loi-tu-cac-thanh-tuu-khoa-hoc\/\" \/>\n<meta property=\"og:locale\" content=\"vi_VN\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"\u201cNg\u01b0\u1eddi ngh\u00e8o c\u0169ng ph\u1ea3i \u0111\u01b0\u1ee3c h\u01b0\u1edfng l\u1ee3i t\u1eeb c\u00e1c th\u00e0nh t\u1ef1u khoa h\u1ecdc\u201d - 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